Introduction

Dr. Sang Hyun Kim is currently a professor in the College of Natural Science at Chonbuk National University. His research focuses on skeletal muscle metabolism (mitochondrial biogenesis), aging, and the development of exercise mimetics for health promotion. He previously worked as a postdoctoral researcher at Washington University School of Medicine in St. Louis and Chungnam National University, and he is now a professor in the Department of Sports Science at Chonbuk National University in Korea.

Education

2005-2009 Keimyung University, Graduate School (Ph.D. in Physical Education)

Work Experience

2005.03-2009.08 Adjunct Faculty (Keimyung University, Keimyung College University)

2010.01 -2014.06. Post-Doc. Washington University School of Medicine in St. Louis

2014.07-2015.06. Post-Doc. Chungnam National University, Department of Sports Science

2015.09-present. Professor Jeonbuk National Universiry, Department of Sport Science

Interests: 

Skeletal muscle, Metabolism, Mitochondrial function, Aging, Sarcopenia, Exercise mimetics, Exercise training

Publications 

< SCI/E Journals >

Wang, Z., et al. (2025). Effects of Combined Exercise Training on Modulating FineParticulate Matter–Induced Skeletal Muscle Damage inOffspring Gestationally Exposed. Journal of Cachexia, Sarcopenia and Muscle.16.5. (Corresponding Author)

Gu, Y., et al. (2025). Global research trends on exercise and circadian rhythm: A bibliometric analysis. Chronobiology International, 1-14. (Corresponding Author)

Liu, W., et al. (2025). PrPC Glycoprotein Is Indispensable for Maintenance of Skeletal Muscle Homeostasis During Aging. Journal of Cachexia, Sarcopenia and Muscle, 16(1), e13706. (Corresponding Author)

Wang, Z., et al. (2025). Combination of intermittent fasting and endurance exercise impedes the development of the musculoskeletal system in non-obese growing rats. Nutrition Research and Practice, 19(4), 483-496. (Corresponding Author)

Liu, W., et al. (2025). Balancing benefits and risks of aerobic exercise for aging and musculoskeletal health. Experimental Gerontology, 204, 112747. (Corresponding Author)

Liu, W., et al. (2024). Exposure of young mice to atmospherically relevant PM2. 5 has sex-dependent long-lasting impacts on the skeletal muscle system. Aging and disease. (Corresponding Author)

Gu, Y., et al. (2024). Exercise improves muscle mitochondrial dysfunction-associated lipid profile under circadian rhythm disturbance. The Korean Journal of Physiology & Pharmacology: Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 28(6), 515-526. (Corresponding Author)

Wang, Z., et al. (2024). Differential Effects of Endurance Exercise on Musculoskeletal and Hematopoietic Modulation in Old Mice. Aging and Disease, 15(2), 755. (Corresponding Author)

Liu, W., et al. (2024). Effects of short-term exercise and endurance training on skeletal muscle mitochondria damage induced by particular matter, atmospherically relevant artificial PM2. 5. Frontiers in Public Health, 12, 1302175. (Corresponding Author)

Seong, D., et al. (2022). The effects of combined aerobic and resistance training program in Korean male youth soccer players. Journal of Men’s Health, 18(5), 115. (Corresponding Author)

Kang, Y. S., et al. (2020). Low-intensity exercise training additionally increases mitochondrial dynamics caused by high-fat diet (HFD) but has no additional effect on mitochondrial biogenesis in fast-twitch muscle by HFD. International Journal of Environmental Research and Public Health, 17(15), 5461. (Corresponding Author)

Kang, Y. S., et al. (2019). Effects of swimming exercise on serum irisin and bone FNDC5 in rat models of high-fat diet-induced osteoporosis. Journal of sports science & medicine, 18(4), 596. (Corresponding Author)

Kim, J. C., et al. (2018). Concurrent treatment with ursolic acid and low-intensity treadmill exercise improves muscle atrophy and related outcomes in rats. The Korean journal of physiology & pharmacology: official journal of the Korean Physiological Society and the Korean Society of Pharmacology  22(4), 427. (Corresponding Author)

Jung, S., et al. (2017). Effect of lithium on the mechanism of glucose transport in skeletal muscles. Journal of nutritional science and vitaminology, 63(6), 365-371. (Co-author)

Kim, J. C., et al. (2017). Inhibition of oxidative stress by antioxidant supplementation does not limit muscle mitochondrial biogenesis or endurance capacity in rats. Journal of nutritional science and vitaminology, 63(5), 277-283. (Corresponding Author)

Bang, H. S., et al. (2017). Ursolic acid supplementation decreases markers of skeletal muscle damage during resistance training in resistance-trained men: a pilot study. The Korean Journal of Physiology & Pharmacology, 21(6), 651-656. (Co-author)

Kim, S. H., et al. (2015). PGC‐1α mediates a rapid, exercise‐induced downregulation of glycogenolysis in rat skeletal muscle. The Journal of physiology, 593(3), 635-643. (First Author)

Kim, K., et al. (2014). Physiological and leukocyte subset responses to exercise and cold exposure in cold-acclimatized skaters. Biology of Sport, 31(1), 39-48. (Co-author)

Higashida, K., et al. (2013). Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation. PLoS biology, 11(7), e1001603. (First Author)

Kim, S. H., (2013). β-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1α in skeletal muscle. American Journal of Physiology-Endocrinology and Metabolism, 304(8), E844-E852. (First Author)

Han, D. H., et al. (2012). Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats. Metabolism, 61(11), 1615-1621. (Co-author)

Higashida, K., et al. (2011). Normal adaptations to exercise despite protection against oxidative stress. American Journal of Physiology-Endocrinology and Metabolism, 301(5), E779-E784. (First Author)

Han, D. H., et al. (2011). Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance. PloS one, 6(5), e19739. (Co-author)

Hancock, C. R., et al. (2011). Does calorie restriction induce mitochondrial biogenesis? A reevaluation. The FASEB Journal, 25(2), 785. (Co-author)

< Scopus/KCI journals >

Effect of Extracellular Vehicles, Including Exercise Mimetics, for Improving Bone Loss Caused by Osteoblast Endoplasmic Reticulum Stress. Exercise Science, 2024. 33(1), 36-45.

Electrical stimulation of skeletal muscle cell increase catalase expression and reduced palmitate induced ER stress. The Korean Society of Sports Science, 2020.  29(1), 649-662. 

Effects of ursolic acid on muscle mass and bone microstructure in rats with casting-induced muscle atrophy. Journal of exercise nutrition & biochemistry, 2019. 23(3), 45. 

Position statement: exercise guidelines to increase peak bone mass in adolescents. Journal of Bone Metabolism, 2019. 26(4), 225. (Co-author)

*Inhibition of RYR channel prevent palmitate-induced ER Ca2+ depletion and mitochondria dysfunction in C2C12 cell. The Korean Journal of Sports Science. 2019. 28(5). 

*The physical characteristics, physical fitness and muscle function according to the grade and soccer position of the middle and high school player. Jorunal of Coaching Development. 2019. 21(2).

*The effect of acceleration stabilization on anterior cruciate ligament reconstruction in taekwondo player –case study- The Korean Journal of Sports Science. 2018. 27(5).

*The effects of high intensity ankle stability exercise of ankle power and posture balance in students with chronic ankle sprain. The Korean Journal of Sports Science. 2018. 27(2).

*Effects of overhead squat exercise on postural correction of elementary school students. The Korean Journal of Growth and Development. 2018. 26(2).

*Effects of swimming exercise on high-fat diet –induced low bone mineral density and trabecular bone microstructure in rats. J Exerc Nutrition Biochem. 2017. 21(2).

*Changes of Traf2 and SIRT1 expression by AICAR and SIRT1 activator in TNF-a induced cardiac hypertrophy. The Journal of Kinesiology. 2017. 19(3).

*Effects of short term spine corrective stabilization exercise on back muscle strength in student’s with chronic back pain. The Korean Journal o Growth and Development. 2017. 25(3).

*The effects of sling exercise and proprioceptive neuromuscular facilitation on foot pressure and range of motion after total knee replacement: case study. The Korea Journal of Sports Science. 2017. 26(5).

*Skeletal muscle glycogen breakdown according to duration of endurance training. The Korean Journal of Sports Medicine. 2016. 34(2).

*How long days it have to mature mitochondrial function after repetitive bouts of prolonged endurance exercise training. The Korean Journal of Physical Education. 2015. 54(2).

*The increased PPARβ/δ by endurance exercise control MEF2A-GLUT4 and mitochodrial enzymes through NRF-1 promoter activity in mouse skeletal muscle. Exercise Science. 2015.24(1).

*Control of GLUT4 biogenesis through PPARδ and MEF2A axis with single bout of low-intensity endurance exercise in rodent skeletal muscle. Exercise Science. 2015. 24(1).

*Changes of bone metabolism based on the different interventions with exercise type or additional intake material in ovariectomized rats. J Exerc Nutr Biochem. 2014. 18(1).

*The effects of exercise and CLA intake on IGF-1 and pro-inflammatory cytokines in atrophied skeletal muscle of rats. Integrative Medicine Research. 2014. 2(4).

*Role of PGC-1α and NT-PGC-1α on 4 weeks endurance exercise induced mitochondrial biogenesis. The Korean Journal of Physical Education. 2013. 52(5).

*The effects of SIRT1 on mitochondrial biogenesis in exercised rat skeletal muscle. The Korean Journal of Physical Education. 2013. 52(3). 

*Effects of resveratrol on AMPK activity and mitochondria biogenesis in skeletal muscle cell. The Korean Journal of Physical Education. 2013. 52(2).

*Mechanism for exercise induced PGC-1α transcription in skeletal muscle. Exercise Science. 2013. 22(3).

*The effects of glycogen supercompensation by single bout of glycogen depletion exercise with normal diet in untrained rat skeletal muscle. Exercise Science. 2013. 22(2).

*Effects PGC-1α expression on glycogenolytic and glycolytic enzymes in rat skeletal muscle. Exercise Science. 2013. 22(4).

*Decreased expression of key glycolytic enzymes are responsible for glycogen sparing adaptation in short-term endurance trained rat skeletal muscles. Exercise Science. 2013. 22(2).

*Role of NT-PGC-1α on endurance exercise induced mitochondiral biogenesis in rat skeletal muscles. Exercise Science. 2012. 21(4).

*The effect of β-AR on mitochondrial biogenesis in rat skeletal muscle. Exercise Science. 2012. 21(3).

*Metabolic adaptation by acute and chronic endurance swim exercise in skeletal muscle. Exercise Science. 2012. 21(3).

*The best loading control in western blot for the verification of adaptive responses of exercise in skeletal muscle. Exercise Science. 2012. 21(1).

*Inhibition of AMP-activated protein kinase by SAMS-GFP peptide attenuates contraction stimulated glucose transport activities in skeletal muscle. Exercise Science. 2011. 20(3).